R-(+)-limonene diastereoselective epoxidation: A minireview about of the synthesis methods

R-(+)-limonene epoxidation has been focused from different synthesis methods. Thanks to the optically active epoxides obtained this reaction are widely employed at industrial level, like: agrochemicals, polymers, cosmetics, pharmaceuticals. A key point found in topic asymmetric induction improve yield diastereomers of 1,2-limonene oxide. Many catalysts have developed for diastereoselective epoxidation, but some oxidation methodology not so useful. The enzymes and Jacobsen´s catalyst presented highest selectivity towards endocyclic diastereomers, while other like metals supported on mesoporous materials were directed one or more products, reducing their potential scaling. Also, it was evidenced that controlling parameters allows segregation homogeneous a phase thus increasing its useful reutilization several cycles. This minireview confronts systems used R-(+)-limonene. Challenges, issues trends said chemical transformation also discussed.